COLUMBIA â A non-lethal pilot study conducted by four MU faculty in the College of Veterinary Medicine resulted in seven beagles being euthanized, MU confirmed this week.
The study, published earlier this year by the American College of Veterinary Ophthalmologists, details how the beaglesâ left eyes were purposely injured and then treated with different chemical solutions to understand the effectiveness of hyaluronic acid, commonly found in topical skin treatments, in healing corneal injuries.
But the 0.2 percent hyaluronic acid solution did not make the healing process any faster in the three dogs in group A, the experimental group, than the three dogs in group B, the control group. The seventh dog was given the standard treatment for corneal wounds, which includes an antibiotic, along with drugs that paralyze and dilate the eyes.
According to the study, the beagles, all females between nine and 12 months, were given socialization time and other care normal to a dog's daily schedule. They were all placed under anesthesia prior to the corneal-wounding procedure and wore Elizabethan collars throughout the study to prevent the dogs from hurting their eyes any further. They underwent examinations after the first six hours and then every 12 hours. The study lasted 96 hours. After the wounds healed, the dogs were euthanized.
The authors of the study acknowledged that their sample size was a âpotential limitation.â Twelve animals in each group would have made the experiment stronger, but giving a pilot study such a large sample was "impractical," according to the study.
Despite the failure in the study, MU spokesman Christian Basi said in an emailed statement that the study was still beneficial in treating eye injuries in dogs and other animals.
âWithout animal research, we would not be able to answer some of the most important medical questions,â the statement read. âAnimal research is only done when scientists believe there is no other way to study the problem, and our researchers respect their research animals greatly and provide the utmost care.â
At the conclusion of most studies, the animals are euthanized and their tissue is kept for future research, according to the American Association for Laboratory Animal Science. In this study, all of the beaglesâ corneas were removed and stored for possible further scientific uses.
The authors of the study did not respond to requests for comment, and Basi would not say why the university decided to euthanize the beagles.
The study was approved by the MU Institutional Animal Care and Use Committee and met guidelines outlined in the Association for Research in Vision and Ophthalmologyâs Statement for the Use of Animals in Ophthalmic and Vision Research, according to the News Bureauâs statement.
In May, the Beagle Freedom Project sued the university for violating the Missouri Sunshine Law after members of the group submitted at least 27 requests for public records. Under the law, the public governmental body can decide to waive or reduce the fee to produce requested documents if they've determined the information was being requested in the interest of the public.
MU allegedly denied the fee waivers and demanded more than $ 82,000 to hand over records on animals used by the School of Medicine, according to previous Missourian reporting.
Not long after, the Los Angeles-based animal rights group, which specializes in rescuing and rehoming animals from laboratories and testing facilities, learned of the study.
Beagle Freedom Project Vice President Kevin Chase, a 15-year veteran in animal activism, said his initial reaction to the study was that it was âabsurd and overly gruesome.â
âIf the University of Missouri would have more transparency to the taxpaying public, then maybe projects like this wouldnât get a rubber stamp (of approval),â he said.
He said that most of the time, lab animals are euthanized since the laboratories do not have the space, resources or time for them following research. Additionally, Chase said, labs don't want to draw public attention to the fact that they are engaging in animal research, which is controversial.
Chase said he and others at the Beagle Freedom Project stumbled upon the study when they were looking at MUâs published research. They were trying to get a sense of the type of research the university performs and how many of its laboratory animals are rescuable. It's part of the organization's initiative, called the Identity Campaign, which allows people to virtually adopt an animal living in a laboratory.
Dan Kolde, a private attorney retained by the Beagle Freedom Project, said the lawsuit is in the early information-gathering phase.
Chase said the organization still hadnât received any documents from the university about any animal.
Some states â California, Minnesota, Connecticut, Nevada and New York â have laws mandating the adoption of lab animals after completing research. Bills are pending in Illinois and Maryland. The other 43 states, Missouri included, donât have any sort of requirement by law.
Beagles make up 96 percent of the dogs used by 383 different laboratories in the U.S. The breed makes up such a large portion because they are naturally very trusting of humans. Six of the beagles used in the MU study were purchased by the university from Covance Laboratory in Cumberland, Virginia.
Basi would not disclose how much the university paid for the beagles. He said in a separate email that the statement was all the information he had.
Both Chase and Kolde said had the Beagle Freedom Project known about the beagles, they couldâve found them new homes easily.
âAll they had to do was not kill them,â Chase said.
They injured their left eye and pour acid in it. That would be absolutely painful and the dogs would end up suffering because of it. They could remove the injured eye. But what kind of life is that? This whole thing testing on these dogs is horrible.
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